Gastrin anticorps (C-Term)

N° du produit ABIN499875

Cet anticorps anti-Gastrin est un anticorps Lapin Polyclonal détectant Gastrin dans WB et EIA. Adapté pour Humain et Souris.

Aperçu rapide pour Gastrin anticorps (C-Term) (ABIN499875)

Antigène: Gastrin (GAST)

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Gastrin est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Détail du produit anti-Gastrin anticorps

Épitope: C-Term

Purification: Affinity chromatography purified via peptide column

Immunogène: GAS antibody was raised against a 15 amino acid peptide from near the carboxy terminus of human GAS.

Isotype: IgG

Information d'application

Indications d'application: ELISA. Western Blot: 1 - 2 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: -20 °C

Stockage commentaire: Store the antibody (in aliquots) at -20 °C.

Détails sur Gastrin

Antigène: Gastrin (GAST)

Autre désignation: GAS

Sujet: Steroid receptor co-activators (SRCs) were initially described as nuclear receptor transcription co-activators, but they have recently been determined to co-regulate transcription initiated by other transcription factors. GAS is a recently identified glutamate-rich protein that interacts with SRC1, but not GRIP1 or AIB1, the other two members of the SRC family. GAS can also interact with the alpha subunit of the estrogen receptor (ERa), but not other receptors such as the retinoic acid receptor a, suggesting the interaction between GAS and ERa is relatively specific. Depletion of GAS by RNA interference in MCF7 cells led to a decrease in the mRNA and protein levels of ER target genes such as pS2, c-Myc and cyclin D1, indicating the role of GAS in the regulation of ER target genes. GAS has also been found to associate with an SET1-like methyltransferase complex specific for H3K4 methylation, suggesting that GAS has multiple roles in transcriptional regulation.Synonyms: Glutamate-rich coactivator interacting with SRC1, PA1, PTIP-associated 1 protein

ID gène: 2716513

NCBI Accession: NP_078792

UniProt: P08315